Across TCGA cell cohorts, ACTRT3 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACTRT3-associated genes across cancer lineages are OR4F4, OR4A47, and OR11H1. Each is linked with ACTRT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACTRT3-to-partner and partner-to-ACTRT3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTRT3→partner) and Y-score (partner→ACTRT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR4F4 →	+0.025	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR4A47 →	+0.022	+5.022	<.001	.002	3	1
BLOOD_Leukemia	OR11H1 →	+0.080	+5.786	<.001	<.001	3	1
BLOOD_Leukemia	SLCO1C1 →	+0.096	+4.705	<.001	.003	3	1
BLOOD_Leukemia	SLC17A4 →	+0.092	+4.152	<.001	.009	3	1
BLOOD_Leukemia	CER1 →	+1.039	+4.152	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

ACTRT3 survival (RNA) · tumor vs normal (RNA) · all ACTRT3 data types