ACTRT2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ACTRT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,679 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ACTRT2-associated GO terms across cancer lineages are Protein insertion into membrane, Epithelial tube formation, and Morphogenesis of embryonic epithelium. Each is linked with ACTRT2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ACTRT2-to-partner and partner-to-ACTRT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein insertion into membrane grouped by ACTRT2-low versus ACTRT2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTRT2→partner) and Y-score (partner→ACTRT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADProtein insertion into membrane →+0.086+0.093<.001.00537
STADEpithelial tube formation →+0.066+0.102<.001<.00137
STADMorphogenesis of embryonic epithelium →+0.063+0.091<.001<.00136
STADTube formation →+0.067+0.098<.001<.00136
KIRPCellular ketone metabolic process →+0.034+0.003<.001.00336
STADTetrapyrrole biosynthetic process →+0.069+0.193<.001.00227
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,679 associations by consensus.

Protein insertion into membrane by ACTRT2 expression — STAD

Box plot of Protein insertion into membrane in ACTRT2-low vs ACTRT2-high samples in STAD.

Explore this box plot interactively →

Exploration