ACTRT2

Across TCGA cell cohorts, ACTRT2 RNA expression is significantly associated with the mutation status of many other genes, with 47 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACTRT2-associated genes across cancer lineages are MRTFB, MORC2, and TOP3A. Each is linked with ACTRT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACTRT2-to-partner and partner-to-ACTRT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRTFB grouped by ACTRT2-low versus ACTRT2-high in BREAST.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTRT2→partner) and Y-score (partner→ACTRT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	MRTFB →	+4.196	+0.013	.006	<.001	3	2
LUNG_NSCLC_LUSC	MORC2 →	+4.643	+0.053	.008	.001	3	1
LUNG_NSCLC_LUSC	TOP3A →	+4.643	+0.053	.008	.001	3	1
LUNG_NSCLC_LUSC	PLXNB2 →	+4.643	+0.053	.008	.001	3	1
LUNG_NSCLC_LUSC	ATG2A →	+4.643	+0.053	.008	.001	3	1
BLOOD_Leukemia	AAGAB →	+5.507	+0.065	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

MRTFB by ACTRT2 expression — BREAST

Explore this box plot interactively →