ACTR5

Across TCGA patient cohorts, ACTR5 protein abundance is significantly associated with the RNA expression of many other genes, with 4,709 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ACTR5-associated genes across cancer lineages are CTNNBL1, H1-5, and RN7SL398P. Each is linked with ACTR5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACTR5-to-partner and partner-to-ACTR5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACTR5 versus CTNNBL1 in BRCA, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR5→partner) and Y-score (partner→ACTR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CTNNBL1 →	+0.403	+0.211	.003	.001	3	3
HNSC	H1-5 →	+1.843	+0.244	<.001	<.001	3	3
UCEC	RN7SL398P →	-1.094	-0.123	<.001	<.001	3	2
BRCA	NFS1 →	+0.450	+0.190	<.001	.002	3	2
BRCA	PPP2R3A →	-0.588	-0.182	.008	.002	3	2
LSCC	ADAM23 →	-2.251	-0.196	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,709 associations by consensus.

ACTR5 vs CTNNBL1 — BRCA

Explore this scatter interactively →