ACTR5

Across TCGA cell cohorts, ACTR5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,394 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACTR5-associated GO terms across cancer lineages are UV-damage excision repair, Promoter clearance during DNA-templated transcription, and RNA polymerase II promoter clearance. Each is linked with ACTR5 in more than 17 cancer types. Because this analysis shows association rather than direction, both ACTR5-to-partner and partner-to-ACTR5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UV-damage excision repair grouped by ACTR5-low versus ACTR5-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR5→partner) and Y-score (partner→ACTR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	UV-damage excision repair →	+0.120	+1.246	<.001	<.001	3	18
SOFT_TISSUE	Promoter clearance during DNA-templated transcription →	+0.108	+0.716	<.001	<.001	3	16
SOFT_TISSUE	RNA polymerase II promoter clearance →	+0.108	+0.716	<.001	<.001	3	16
PANCREAS	Regulation of centriole-centriole cohesion →	+0.164	+0.754	<.001	<.001	3	15
BONE	Chromosome separation →	+0.159	+0.799	.003	<.001	3	15
BONE	Telomere maintenance in response to DNA damage →	+0.107	+0.650	.007	.009	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,394 associations by consensus.

UV-damage excision repair by ACTR5 expression — STOMACH

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