ACTR3P2

Across TCGA pan-cancer cohorts, ACTR3P2 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ACTR3P2 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ACTR3P2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ACTR3P2 expression acts as an unfavorable survival marker, although some lineages such as UCEC and KIRC show a favorable association.

UCEC, BRCA, and STAD are the cancer types where ACTR3P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	IV	0.713	0.276	.007	42	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	36	view →
STAD	DFS	Median	IV	0.208	0.569	.011	34	view →
KIRC	DFS	Tertile	All	0.696	0.589	.020	28	view →
LUSC	OS	Quartile	II,III,IV	0.556	0.305	.002	25	view →
ACC	OS	Quartile	All	0.678	0.913	.001	21	view →
LGG	DFS	Tertile	All	0.748	0.869	.016	15	view →
SKCM	OS	Tertile	All	0.842	0.759	.002	12	view →
BLCA	OS	Tertile	IV	0.415	0.637	.009	12	view →
CESC	OS	Quartile	IV	0.143	0.646	<.001	12	view →
COAD	OS	Median	All	0.910	0.827	.023	9	view →
GBM	DFS	Median	All	0.178	0.298	.004	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ACTR3P2–UCEC (DFS)

Open the UCEC breakdown →