ACTR3BP6

Across TCGA pan-cancer cohorts, ACTR3BP6 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated ACTR3BP6 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ACTR3BP6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ACTR3BP6 expression acts as an unfavorable survival marker.

COAD, LUAD, and MESO are the cancer types where ACTR3BP6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	All	0.045	0.871	<.001	144	view →
LUAD	OS	Tertile	II,III,IV	0.111	0.750	<.001	87	view →
MESO	OS	Tertile	All	0.130	0.557	.019	54	view →
THCA	DFS	Tertile	II,III,IV	0.095	0.730	.002	54	view →
ACC	DFS	Tertile	All	0.057	0.667	<.001	45	view →
SKCM	DFS	Tertile	II,III,IV	0.040	0.691	<.001	36	view →
KIRC	DFS	Tertile	IV	0.090	0.620	<.001	36	view →
LUSC	OS	Tertile	II,III,IV	0.054	0.780	<.001	36	view →
LIHC	DFS	Tertile	III,IV	0.040	0.361	<.001	18	view →
GBM	DFS	Tertile	All	0.068	0.288	.003	9	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

ACTR3BP6–COAD (OS)

Open the COAD breakdown →