Across TCGA patient cohorts, ACTR3BP2 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACTR3BP2-associated genes across cancer lineages are MIR6857, RNU6-1336P, and SNORA48B. Each is linked with ACTR3BP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACTR3BP2-to-partner and partner-to-ACTR3BP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR3BP2→partner) and Y-score (partner→ACTR3BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6857 →	+0.817	+5.358	<.001	.006	3	1
UCEC	RNU6-1336P →	+0.758	+4.982	<.001	.009	3	1
UCEC	SNORA48B →	+0.612	+5.299	<.001	.006	3	1
UCEC	RNU6-316P →	+0.748	+6.123	<.001	.002	3	1
UCEC	RPL31P54 →	+0.405	+5.420	<.001	.005	3	1
UCEC	LINC02144 →	+0.267	+5.852	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

ACTR3BP2 survival (RNA) · tumor vs normal (RNA) · all ACTR3BP2 data types