ACTR3BP1

Across TCGA pan-cancer cohorts, ACTR3BP1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated ACTR3BP1 data layer.

The strongest signal is observed in thymoma (THYM), where higher ACTR3BP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ACTR3BP1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

THYM, STAD, and HNSC are the cancer types where ACTR3BP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Tertile	All	0.169	0.931	<.001	75	view →
STAD	DFS	Tertile	All	0.353	0.733	<.001	72	view →
HNSC	DFS	Tertile	IV	1.000	0.310	.018	60	view →
UCEC	OS	Tertile	All	0.351	0.683	<.001	54	view →
KIRP	OS	Tertile	All	0.590	0.903	.001	45	view →
SKCM	OS	Tertile	All	0.086	0.342	.003	42	view →
KICH	DFS	Tertile	All	0.102	0.848	.004	39	view →
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
KIRC	OS	Tertile	All	0.385	0.662	.013	36	view →
LUAD	OS	Tertile	All	0.254	0.697	.020	18	view →
THCA	DFS	Tertile	All	0.040	0.828	<.001	18	view →
TGCT	DFS	Tertile	All	0.014	0.837	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

ACTR3BP1–THYM (OS)

Open the THYM breakdown →