ACTR3B

Across TCGA patient cohorts, ACTR3B protein abundance is significantly associated with the RNA expression of many other genes, with 7,352 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ACTR3B-associated genes across cancer lineages are CCN4, CCRL2, and FGFBP1. Each is linked with ACTR3B in more than 2 cancer types. Because this analysis shows association rather than direction, both ACTR3B-to-partner and partner-to-ACTR3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACTR3B versus CCN4 in OV, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR3B→partner) and Y-score (partner→ACTR3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCN4 →	-1.733	-0.843	<.001	<.001	3	3
UCEC	CCRL2 →	-0.684	-0.372	<.001	<.001	3	3
LSCC	FGFBP1 →	-1.328	-0.155	.001	.009	3	3
UCEC	NAPEPLD →	+0.677	+0.401	<.001	.001	3	3
GBM	HSPA12A →	+0.672	+0.571	<.001	<.001	3	3
OV	ARMC10 →	+0.380	+0.685	.009	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,352 associations by consensus.

ACTR3B vs CCN4 — OV

Explore this scatter interactively →