ACTR2

Across TCGA patient cohorts, ACTR2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,834 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ACTR2-associated proteins across cancer lineages are TXNDC9, ARPC5, and KIF3A_T633. Each is linked with ACTR2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ACTR2-to-partner and partner-to-ACTR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACTR2 versus TXNDC9 in PDAC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR2→partner) and Y-score (partner→ACTR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TXNDC9 →	+0.240	+0.276	<.001	.001	3	6
GBM	ARPC5 →	+0.253	+0.224	<.001	<.001	3	5
UCEC	KIF3A_T633 →	-0.663	-0.394	.002	<.001	3	4
LSCC	SPAST →	+0.435	+0.320	<.001	.002	2	5
GBM	ARPC1B →	+0.483	+0.274	.003	.002	3	4
GBM	CAPZA1 →	+0.315	+0.346	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,834 associations by consensus.

ACTR2 vs TXNDC9 — PDAC

Explore this scatter interactively →