ACTR2

Across TCGA patient cohorts, ACTR2 protein abundance is significantly associated with the RNA expression of many other genes, with 22,522 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACTR2-associated genes across cancer lineages are ARHGAP25, LAIR1, and ARHGAP30. Each is linked with ACTR2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ACTR2-to-partner and partner-to-ACTR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACTR2 versus ARHGAP25 in OV, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR2→partner) and Y-score (partner→ACTR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ARHGAP25 →	+0.699	+0.203	<.001	<.001	3	10
GBM	LAIR1 →	+1.361	+0.245	<.001	<.001	3	10
GBM	ARHGAP30 →	+1.056	+0.227	<.001	<.001	3	10
GBM	SIRPB2 →	+1.176	+0.201	<.001	<.001	3	10
GBM	LINC01094 →	+0.661	+0.127	<.001	<.001	3	10
GBM	SPI1 →	+1.128	+0.200	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,522 associations by consensus.

ACTR2 vs ARHGAP25 — OV

Explore this scatter interactively →