ACTR1B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ACTR1B protein abundance is significantly associated with the RNA expression of many other genes, with 11,042 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ACTR1B-associated genes across cancer lineages are CDCA5, CCNB1, and SKA1. Each is linked with ACTR1B in more than 5 cancer types. Because this analysis shows association rather than direction, both ACTR1B-to-partner and partner-to-ACTR1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACTR1B versus CDCA5 in BRCA, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR1B→partner) and Y-score (partner→ACTR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACDCA5 →-0.863-0.289.001<.00136
LUADCCNB1 →-0.989-0.232<.001<.00136
LUADSKA1 →-0.972-0.244<.001<.00136
CCRCCTEF →+0.951+0.259<.001<.00136
BRCAAURKB →-1.157-0.266<.001<.00136
LUADTRIP13 →-1.019-0.236<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,042 associations by consensus.

ACTR1B vs CDCA5 — BRCA

Per-sample scatter of ACTR1B vs CDCA5 in BRCA (Pearson r = -0.33).

Explore this scatter interactively →

Exploration