ACTR1B

Across TCGA patient cohorts, ACTR1B mutation is significantly associated with the RNA expression of many other genes, with 1,115 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACTR1B-associated genes across cancer lineages are TRABD, TXN2, and TAF9. Each is linked with ACTR1B in more than 2 cancer types. Because this analysis shows association rather than direction, both ACTR1B-to-partner and partner-to-ACTR1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRABD grouped by ACTR1B-low versus ACTR1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR1B→partner) and Y-score (partner→ACTR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRABD →	+0.465	+3.491	.009	.002	3	3
UCEC	TXN2 →	+0.347	+3.003	.006	<.001	3	3
UCEC	TAF9 →	+0.635	+2.906	<.001	.002	3	2
UCEC	TUBGCP5 →	+0.448	+2.939	.004	<.001	3	2
UCEC	STMN1P1 →	+0.354	+2.845	.005	.004	3	2
UCEC	TRMU →	+0.631	+4.000	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,115 associations by consensus.

TRABD by ACTR1B expression — UCEC

Explore this box plot interactively →