ACTR1B

Across TCGA cell cohorts, ACTR1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,156 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACTR1B-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Post-Golgi vesicle-mediated transport, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with ACTR1B in more than 12 cancer types. Because this analysis shows association rather than direction, both ACTR1B-to-partner and partner-to-ACTR1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ACTR1B-low versus ACTR1B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR1B→partner) and Y-score (partner→ACTR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.172	+0.845	<.001	<.001	3	13
OESOPHAGUS	Post-Golgi vesicle-mediated transport →	+0.065	+1.029	.004	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.136	+0.750	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.134	+0.879	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.064	+0.879	<.001	.001	3	11
OESOPHAGUS	Mitochondrial electron transport, cytochrome c to oxygen →	+0.122	+0.991	.004	.005	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,156 associations by consensus.

Negative regulation of myoblast fusion by ACTR1B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →