ACTR1A

Across TCGA patient cohorts, ACTR1A mutation is significantly associated with the RNA expression of many other genes, with 1,871 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACTR1A-associated genes across cancer lineages are LINC00428, RNU6-532P, and SNORD116-10. Each is linked with ACTR1A in more than 1 cancer types. Because this analysis shows association rather than direction, both ACTR1A-to-partner and partner-to-ACTR1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00428 grouped by ACTR1A-low versus ACTR1A-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR1A→partner) and Y-score (partner→ACTR1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC00428 →	+0.225	+5.306	<.001	.006	3	2
BRCA	RNU6-532P →	+0.171	+7.471	<.001	.008	3	2
SKCM	SNORD116-10 →	+0.519	+6.624	<.001	.001	3	2
CESC	RNU6-1220P →	+0.408	+6.837	<.001	<.001	3	1
CESC	MIR4662B →	+0.529	+5.539	<.001	.004	3	1
UCEC	MIR98 →	+0.189	+2.064	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,871 associations by consensus.

LINC00428 by ACTR1A expression — CESC

Explore this box plot interactively →