ACTR10

Across TCGA patient cohorts, ACTR10 mutation is significantly associated with the RNA expression of many other genes, with 526 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACTR10-associated genes across cancer lineages are OR9Q2, MIR6765, and OR10J3. Each is linked with ACTR10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACTR10-to-partner and partner-to-ACTR10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR9Q2 grouped by ACTR10-low versus ACTR10-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR10→partner) and Y-score (partner→ACTR10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR9Q2 →	+0.072	+5.721	<.001	.001	3	2
CESC	MIR6765 →	+0.418	+5.201	<.001	.007	3	2
BLCA	OR10J3 →	+0.110	+4.497	<.001	.009	3	2
LUSC	CD24P1 →	+0.144	+4.150	.009	.003	3	2
UCEC	CCL5 →	+1.354	+3.475	<.001	.002	3	1
UCEC	CWC25 →	+0.487	+3.716	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 526 associations by consensus.

OR9Q2 by ACTR10 expression — COAD

Explore this box plot interactively →