ACTR10

Across TCGA cell cohorts, ACTR10 mutation is significantly associated with the mutation status of many other genes, with 1,692 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACTR10-associated genes across cancer lineages are BAZ2A, MTMR3, and GINS1. Each is linked with ACTR10 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACTR10-to-partner and partner-to-ACTR10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BAZ2A grouped by ACTR10-low versus ACTR10-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTR10→partner) and Y-score (partner→ACTR10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	BAZ2A →	+3.390	+5.080	<.001	<.001	1	3
BLOOD_Leukemia	MTMR3 →	+5.560	+4.736	.003	.003	1	2
LARGE_INTESTINE	GINS1 →	+5.087	+4.523	.006	.006	1	2
BLOOD_Leukemia	CSNK2A1 →	+5.560	+4.736	.003	.003	1	2
BLOOD_Leukemia	ABCD1 →	+3.145	+3.932	.004	.004	1	2
BLOOD_Leukemia	BMX →	+4.560	+4.309	.007	.007	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,692 associations by consensus.

BAZ2A by ACTR10 expression — BLOOD_Leukemia

Explore this box plot interactively →