ACTL9

Across TCGA cell cohorts, ACTL9 protein abundance is significantly associated with the RNA expression of many other genes, with 1,386 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACTL9-associated genes across cancer lineages are TMED5, MUTYH, and MAPKAPK2. Each is linked with ACTL9 in more than 4 cancer types. Because this analysis shows association rather than direction, both ACTL9-to-partner and partner-to-ACTL9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACTL9 versus TMED5 in BLOOD_Leukemia, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTL9→partner) and Y-score (partner→ACTL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TMED5 →	+0.796	+1.554	.002	<.001	3	5
BLOOD_Leukemia	MUTYH →	+0.996	+1.512	<.001	.001	3	4
BLOOD_Leukemia	MAPKAPK2 →	-1.233	-1.805	.003	.001	3	4
LUNG_SCLC	SLC49A4 →	+0.984	+1.625	.008	.008	3	3
LUNG_SCLC	PKN2 →	+1.070	+1.945	<.001	.002	3	3
BLOOD_Leukemia	CCDC18 →	+1.080	+1.478	.008	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,386 associations by consensus.

ACTL9 vs TMED5 — BLOOD_Leukemia

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