ACTL9

Across TCGA cell cohorts, ACTL9 protein abundance is significantly associated with the go_rna of many other GO terms, with 778 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACTL9-associated GO terms across cancer lineages are Autophagosome organization, Thyroid hormone generation, and Autophagosome assembly. Each is linked with ACTL9 in more than 3 cancer types. Because this analysis shows association rather than direction, both ACTL9-to-partner and partner-to-ACTL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagosome organization grouped by ACTL9-low versus ACTL9-high in LUNG_SCLC.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTL9→partner) and Y-score (partner→ACTL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Autophagosome organization →	+0.045	+1.608	.006	<.001	3	4
LIVER	Thyroid hormone generation →	-0.234	-0.884	.007	.007	3	4
LUNG_SCLC	Autophagosome assembly →	+0.046	+1.608	.002	<.001	3	3
BLOOD_Leukemia	Protein insertion into mitochondrial inner membrane from matrix →	-0.055	-1.246	.008	.001	3	3
UPPER_AERODIGESTIVE_TRACT	rRNA pseudouridine synthesis →	-0.097	-2.519	.002	.001	3	3
STOMACH	UDP-alpha-D-glucose metabolic process →	+0.085	+1.246	.009	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 778 associations by consensus.

Autophagosome organization by ACTL9 expression — LUNG_SCLC

Explore this box plot interactively →