ACTL6B

Across TCGA patient cohorts, ACTL6B RNA expression is significantly associated with the protein abundance of many other proteins, with 12,581 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ACTL6B-associated proteins across cancer lineages are STT3A, RPN2, and SEC24A. Each is linked with ACTL6B in more than 3 cancer types. Because this analysis shows association rather than direction, both ACTL6B-to-partner and partner-to-ACTL6B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACTL6B versus STT3A in PDAC, with a Pearson correlation of -0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTL6B→partner) and Y-score (partner→ACTL6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	STT3A →	-0.383	-0.221	.009	.007	3	4
GBM	RPN2 →	-0.290	-1.449	<.001	<.001	3	3
LSCC	SEC24A →	-0.266	-0.129	<.001	.001	3	3
PDAC	ITGB1_T777 →	-0.600	-0.369	<.001	.001	3	3
CCRCC	ANKRD13A →	-0.203	-0.058	.005	.004	3	3
GBM	LMAN1 →	-0.322	-1.347	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,581 associations by consensus.

ACTL6B vs STT3A — PDAC

Explore this scatter interactively →