ACTL6B

Across TCGA patient cohorts, ACTL6B protein abundance is significantly associated with the RNA expression of many other genes, with 6,155 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ACTL6B-associated genes across cancer lineages are DLX2, FKBP1B, and EHD3. Each is linked with ACTL6B in more than 1 cancer types. Because this analysis shows association rather than direction, both ACTL6B-to-partner and partner-to-ACTL6B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACTL6B versus DLX2 in BRCA, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTL6B→partner) and Y-score (partner→ACTL6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DLX2 →	+1.947	+1.688	.003	.004	3	2
BRCA	FKBP1B →	+0.727	+1.234	.007	.005	3	2
BRCA	EHD3 →	+0.800	+1.189	.008	.007	3	2
BRCA	FAIM2 →	+3.143	+2.219	.001	.002	3	2
BRCA	EDIL3 →	+4.136	+2.123	.001	.007	3	2
BRCA	CARTPT →	+9.271	+2.061	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,155 associations by consensus.

ACTL6B vs DLX2 — BRCA

Explore this scatter interactively →