ACTG2

Across TCGA patient cohorts, ACTG2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,191 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACTG2-associated genes across cancer lineages are CNN1, MYH11, and TSPAN2. Each is linked with ACTG2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ACTG2-to-partner and partner-to-ACTG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACTG2 versus CNN1 in UCEC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTG2→partner) and Y-score (partner→ACTG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CNN1 →	+2.307	+0.905	<.001	<.001	3	7
COAD	MYH11 →	+1.859	+0.724	<.001	<.001	3	6
CCRCC	TSPAN2 →	+1.322	+1.118	.001	.005	2	6
LSCC	ITGA11 →	+1.114	+0.756	<.001	<.001	3	5
UCEC	MYL9 →	+1.107	+0.773	<.001	<.001	3	5
COAD	WFDC1 →	+0.720	+0.843	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,191 associations by consensus.

ACTG2 vs CNN1 — UCEC

Explore this scatter interactively →