ACTG2

Across TCGA patient cohorts, ACTG2 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACTG2-associated genes across cancer lineages are Hepatocytes, MPP, and Platelets. Each is linked with ACTG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACTG2-to-partner and partner-to-ACTG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hepatocytes grouped by ACTG2-low versus ACTG2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTG2→partner) and Y-score (partner→ACTG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Hepatocytes →	+0.026	+2.828	<.001	.036	3	2
COAD	MPP →	+0.027	+3.403	.013	.035	3	1
HNSC	Platelets →	+0.032	+4.100	<.001	.029	3	1
UCEC	Pericytes →	+0.040	+2.113	.014	.044	3	1
UCEC	pDC →	+0.076	+2.818	.011	.037	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Hepatocytes by ACTG2 expression — UCEC

Explore this box plot interactively →