ACTG2

Across TCGA cell cohorts, ACTG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,084 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ACTG2-associated GO terms across cancer lineages are Cellular response to transforming growth factor beta stimulus, Mesenchyme migration, and Response to fluoride. Each is linked with ACTG2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ACTG2-to-partner and partner-to-ACTG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to transforming growth factor beta stimulus grouped by ACTG2-low versus ACTG2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTG2→partner) and Y-score (partner→ACTG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Cellular response to transforming growth factor beta stimulus →	+0.084	+0.198	<.001	<.001	3	6
BREAST	Mesenchyme migration →	+1.367	+3.720	<.001	<.001	3	6
KIDNEY	Response to fluoride →	+0.166	+1.302	.003	.009	2	7
KIDNEY	Regulation of miRNA-mediated gene silencing →	+0.065	+1.313	<.001	.008	3	5
PANCREAS	Response to transforming growth factor beta →	+0.063	+0.181	<.001	<.001	3	5
LUNG_NSCLC_LUAD	Positive regulation of protein localization to nucleus →	+0.046	+0.294	.007	.008	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,084 associations by consensus.

Cellular response to transforming growth factor beta stimulus by ACTG2 expression — PANCREAS

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