Across TCGA pan-cancer cohorts, ACTG1P3 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated ACTG1P3 data layer.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ACTG1P3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ACTG1P3 expression acts as an unfavorable survival marker, although some lineages such as UCS and READ show a favorable association.
KIRC, KIRP, and UVM are the cancer types where ACTG1P3 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.