ACTG1P25

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ACTG1P25 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACTG1P25-associated genes across cancer lineages are Mesangial cells, pDC, and MSC. Each is linked with ACTG1P25 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACTG1P25-to-partner and partner-to-ACTG1P25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesangial cells grouped by ACTG1P25-low versus ACTG1P25-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTG1P25→partner) and Y-score (partner→ACTG1P25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMesangial cells →-0.058-3.448.003.00531
UCECpDC →+0.053+3.202.031.00931
UCECMSC →+0.210+2.321.045.03621
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Mesangial cells by ACTG1P25 expression — UCEC

Box plot of Mesangial cells in ACTG1P25-low vs ACTG1P25-high samples in UCEC.

Explore this box plot interactively →

Exploration