ACTG1P22

Across TCGA pan-cancer cohorts, ACTG1P22 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated ACTG1P22 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ACTG1P22 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ACTG1P22 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

HNSC, SKCM, and KIRP are the cancer types where ACTG1P22 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	III,IV	0.498	0.278	<.001	131	view →
SKCM	OS	Median	All	0.402	0.279	<.001	104	view →
KIRP	DFS	Quartile	All	0.686	0.898	<.001	73	view →
UVM	OS	Tertile	III,IV	0.070	0.843	<.001	60	view →
KIRC	OS	Tertile	All	0.558	0.738	<.001	48	view →
LUAD	OS	Median	II,III,IV	0.867	0.641	<.001	43	view →
ESCA	OS	Tertile	II,III,IV	0.638	0.319	.002	36	view →
UCS	DFS	Tertile	II,III,IV	0.547	0.182	.012	34	view →
CHOL	DFS	Tertile	All	0.840	0.223	.001	22	view →
READ	DFS	Median	IV	0.179	0.936	.010	20	view →
LIHC	DFS	Tertile	III,IV	0.638	0.252	.018	18	view →
ACC	DFS	Tertile	IV	0.047	0.339	.042	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

ACTG1P22–HNSC (OS)

Open the HNSC breakdown →