ACTG1P19

Across TCGA pan-cancer cohorts, ACTG1P19 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated ACTG1P19 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher ACTG1P19 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ACTG1P19 expression acts as an unfavorable survival marker, although some lineages such as ESCA and LUSC show a favorable association.

KICH, DLBC, and LGG are the cancer types where ACTG1P19 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	II,III,IV	0.500	1.000	<.001	64	view →
DLBC	DFS	Median	IV	0.128	1.000	.017	33	view →
LGG	DFS	Tertile	All	0.766	0.875	.004	30	view →
ESCA	OS	Tertile	IV	0.738	0.143	.024	18	view →
UCS	OS	Median	III,IV	0.194	0.529	.017	18	view →
LUAD	DFS	Median	All	0.697	0.818	.004	17	view →
LUSC	DFS	Median	II,III,IV	0.780	0.630	.010	16	view →
STAD	DFS	Tertile	II,III,IV	0.440	0.570	.017	15	view →
CESC	DFS	Tertile	IV	0.592	0.083	.035	12	view →
UVM	DFS	Tertile	II,III,IV	0.437	0.779	.018	11	view →
BLCA	OS	Tertile	III,IV	0.414	0.141	.028	10	view →
THCA	OS	Tertile	IV	0.561	1.000	.004	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

ACTG1P19–KICH (DFS)

Open the KICH breakdown →