ACTG1P16

Across TCGA pan-cancer cohorts, ACTG1P16 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of ACTG1P16’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ACTG1P16 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ACTG1P16 is over-expressed in tumor.

COAD, BRCA, and HNSC are the cancer types where ACTG1P16 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ACTG1P16 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.277	.001	6	view →
BRCA	All	II,III,IV	+0.044	<.001	4	view →
HNSC	All	All	+0.044	.015	2	view →
LUSC	All	All	+0.045	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

ACTG1P16–COAD

Open the COAD breakdown →