ACTG1P15

Across TCGA pan-cancer cohorts, ACTG1P15 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ACTG1P15 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher ACTG1P15 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ACTG1P15 expression acts as an unfavorable survival marker, although some lineages such as SKCM and LIHC show a favorable association.

KICH, STAD, and SKCM are the cancer types where ACTG1P15 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	III,IV	0.160	0.931	<.001	96	view →
STAD	DFS	Quartile	II,III,IV	0.514	0.713	.001	46	view →
SKCM	OS	Tertile	III,IV	0.886	0.729	.001	35	view →
LIHC	OS	Median	All	0.642	0.356	<.001	24	view →
KIRP	DFS	Median	III,IV	0.356	0.887	.001	23	view →
LUSC	DFS	Tertile	II,III,IV	0.346	0.779	.001	20	view →
ACC	OS	Quartile	II,III,IV	0.541	1.000	.001	20	view →
LUAD	DFS	Tertile	IV	0.360	0.693	.011	19	view →
PRAD	DFS	Tertile	All	0.829	0.919	.009	14	view →
UCS	DFS	Tertile	IV	0.975	0.361	.024	12	view →
BRCA	DFS	Tertile	II,III,IV	0.927	0.961	.017	9	view →
THYM	DFS	Quartile	III,IV	1.000	0.351	.016	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ACTG1P15–KICH (DFS)

Open the KICH breakdown →