ACTG1P14

Across TCGA pan-cancer cohorts, ACTG1P14 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of ACTG1P14’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ACTG1P14 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ACTG1P14 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

HNSC, BRCA, and COAD are the cancer types where ACTG1P14 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ACTG1P14 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	II,III,IV	+0.432	<.001	6	view →
BRCA	All	All	+0.135	.004	6	view →
COAD	Female	All	+0.830	<.001	4	view →
KIRP	All	II,III,IV	+0.218	.011	4	view →
THCA	All	All	−0.244	.005	3	view →
KICH	All	All	−0.137	.020	2	view →
KIRC	All	All	+0.118	.006	2	view →
CHOL	All	All	+0.309	.039	1	view →
LIHC	All	II,III,IV	+0.111	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

ACTG1P14–HNSC

Open the HNSC breakdown →