ACTG1P13

Across TCGA pan-cancer cohorts, ACTG1P13 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated ACTG1P13 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher ACTG1P13 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ACTG1P13 expression acts as an unfavorable survival marker, although some lineages such as BLCA and GBM show a favorable association.

LUSC, STAD, and HNSC are the cancer types where ACTG1P13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	III,IV	0.162	0.669	<.001	108	view →
STAD	DFS	Tertile	All	0.279	0.725	.001	54	view →
HNSC	DFS	Tertile	III,IV	0.359	0.628	.003	54	view →
BLCA	OS	Tertile	II,III,IV	1.000	0.707	.023	42	view →
COAD	OS	Tertile	III,IV	0.159	0.692	.021	36	view →
KIRP	OS	Tertile	II,III,IV	0.111	0.769	<.001	36	view →
KIRC	OS	Tertile	All	0.430	0.676	.004	36	view →
TGCT	OS	Tertile	All	0.690	0.968	<.001	36	view →
GBM	DFS	Tertile	All	0.575	0.236	.006	30	view →
UCEC	DFS	Tertile	All	0.260	0.660	.020	30	view →
CHOL	OS	Tertile	All	0.089	0.727	.001	27	view →
THCA	OS	Tertile	IV	0.813	1.000	.039	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

ACTG1P13–LUSC (DFS)

Open the LUSC breakdown →