ACTG1P1

Across TCGA pan-cancer cohorts, ACTG1P1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ACTG1P1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher ACTG1P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ACTG1P1 expression acts as an unfavorable survival marker, although some lineages such as UVM and UCS show a favorable association.

THCA, UVM, and STAD are the cancer types where ACTG1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Median	II,III,IV	0.326	1.000	.001	61	view →
UVM	DFS	Median	II,III,IV	0.922	0.520	<.001	53	view →
STAD	DFS	Quartile	IV	0.146	0.853	.001	45	view →
UCS	DFS	Tertile	II,III,IV	0.644	0.148	.001	42	view →
CESC	DFS	Median	II,III,IV	0.709	0.855	.009	34	view →
MESO	OS	Quartile	IV	0.344	0.894	.010	21	view →
KIRC	DFS	Median	All	0.723	0.527	.004	21	view →
LUSC	DFS	Median	III,IV	0.551	0.747	.013	17	view →
ACC	OS	Quartile	III,IV	1.000	0.572	.013	14	view →
ESCA	DFS	Quartile	II,III,IV	0.385	0.677	.004	12	view →
LIHC	DFS	Quartile	All	0.333	0.595	.007	12	view →
HNSC	DFS	Quartile	All	0.632	0.848	.006	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ACTG1P1–THCA (OS)

Open the THCA breakdown →