Across TCGA patient cohorts, ACTG1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,245 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACTG1-associated proteins across cancer lineages are CDKN1B_S10, CRELD2, and FOSL2. Each is linked with ACTG1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ACTG1-to-partner and partner-to-ACTG1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTG1→partner) and Y-score (partner→ACTG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CDKN1B_S10 →	-0.569	-0.535	<.001	<.001	3	5
LSCC	CRELD2 →	-0.475	-0.501	<.001	<.001	3	5
GBM	FOSL2 →	+0.574	+0.473	<.001	<.001	3	5
PDAC	FOSL2_S200 →	+0.485	+0.295	.003	.002	3	5
PDAC	FOSL2_S230 →	+0.566	+0.425	<.001	<.001	3	5
LUAD	RAP1GAP_S515 →	-0.603	-0.366	.004	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,245 associations by consensus.

Exploration

ACTG1 survival (RNA) · tumor vs normal (RNA) · all ACTG1 data types