Across TCGA patient cohorts, ACTG1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,075 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ACTG1-associated genes across cancer lineages are FCGR3B, S100A12, and CXCR1. Each is linked with ACTG1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ACTG1-to-partner and partner-to-ACTG1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTG1→partner) and Y-score (partner→ACTG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FCGR3B →	-1.372	-0.876	<.001	<.001	3	4
GBM	S100A12 →	-1.127	-0.271	<.001	.002	3	4
GBM	CXCR1 →	-1.128	-0.327	<.001	<.001	3	4
BRCA	DNM3OS →	+0.947	+0.288	<.001	.003	3	4
HNSC	FFAR2 →	-1.175	-0.620	<.001	.004	3	4
PDAC	ZNF423 →	+0.531	+0.691	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,075 associations by consensus.

Exploration

ACTG1 survival (RNA) · tumor vs normal (RNA) · all ACTG1 data types