Across TCGA cell cohorts, ACTG1 mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ACTG1-associated genes across cancer lineages are INSM2, TCP11X1, and RCVRN. Each is linked with ACTG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACTG1-to-partner and partner-to-ACTG1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTG1→partner) and Y-score (partner→ACTG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	INSM2 →	+0.170	+3.769	.001	.008	3	2
SOFT_TISSUE	TCP11X1 →	+0.006	+5.977	<.001	.001	3	1
BREAST	RCVRN →	+0.126	+4.199	.006	.007	3	1
BREAST	OR2S2 →	+0.070	+4.199	.009	.007	3	1
BLOOD_Lymphoma	FGF21 →	+0.120	+2.956	<.001	.008	3	1
BLOOD_Lymphoma	RBPJL →	+0.149	+4.017	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

ACTG1 survival (RNA) · tumor vs normal (RNA) · all ACTG1 data types