ACTE1P

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ACTE1P Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ACTE1P data layer compared with 20 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher ACTE1P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ACTE1P expression acts as an unfavorable survival marker.

CESC are the cancer types where ACTE1P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CESCOSMedianAll0.2610.798.00612view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

ACTE1P–CESC (OS)

Kaplan–Meier survival curve for ACTE1P mutant vs wild-type samples in CESC.

Open the CESC breakdown →

Exploration