ACTE1P

Across TCGA patient cohorts, ACTE1P mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACTE1P-associated genes across cancer lineages are ATF4P2, NF1P10, and RNU6-502P. Each is linked with ACTE1P in more than 1 cancer types. Because this analysis shows association rather than direction, both ACTE1P-to-partner and partner-to-ACTE1P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATF4P2 grouped by ACTE1P-low versus ACTE1P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTE1P→partner) and Y-score (partner→ACTE1P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATF4P2 →	+0.094	+5.599	<.001	<.001	3	1
UCEC	NF1P10 →	+0.240	+5.193	.003	<.001	3	1
UCEC	RNU6-502P →	+0.549	+4.538	<.001	.006	3	1
UCEC	RNA5SP124 →	+0.689	+4.581	<.001	.001	3	1
UCEC	RNA5SP319 →	+0.643	+4.061	.004	.005	3	1
UCEC	SNORD90 →	+0.495	+3.840	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

ATF4P2 by ACTE1P expression — UCEC

Explore this box plot interactively →