ACTC1

Across TCGA cell cohorts, ACTC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,725 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ACTC1-associated GO terms across cancer lineages are Regulation of actomyosin structure organization, Potassium ion transmembrane transport, and Positive regulation of supramolecular fiber organization. Each is linked with ACTC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ACTC1-to-partner and partner-to-ACTC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of actomyosin structure organization grouped by ACTC1-low versus ACTC1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTC1→partner) and Y-score (partner→ACTC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of actomyosin structure organization →	+0.051	+0.370	.004	.006	3	8
UPPER_AERODIGESTIVE_TRACT	Potassium ion transmembrane transport →	-0.063	-0.526	.001	.004	3	7
BREAST	Positive regulation of supramolecular fiber organization →	+0.065	+0.371	.001	.006	3	7
BONE	Positive regulation of stress fiber assembly →	+0.181	+1.263	<.001	.007	3	7
SOFT_TISSUE	Spliceosomal tri-snRNP complex assembly →	+0.074	+4.003	<.001	<.001	3	7
BREAST	Potassium ion transport →	-0.065	-0.304	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,725 associations by consensus.

Regulation of actomyosin structure organization by ACTC1 expression — BREAST

Explore this box plot interactively →