Across TCGA pan-cancer cohorts, ACTBP14 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of ACTBP14’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where ACTBP14 RNA is repressed in tumor relative to normal tissue. In most cancer types ACTBP14 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.
THCA, HNSC, and KICH are the cancer types where ACTBP14 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ACTBP14 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.