ACTBP12

Across TCGA pan-cancer cohorts, ACTBP12 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ACTBP12 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ACTBP12 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ACTBP12 expression acts as an unfavorable survival marker, although some lineages such as COAD and CESC show a favorable association.

COAD, STAD, and LUAD are the cancer types where ACTBP12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.568	0.464	.012	28	view →
STAD	DFS	Tertile	IV	0.123	0.703	.006	21	view →
LUAD	DFS	Tertile	IV	0.565	0.926	.020	19	view →
CESC	DFS	Tertile	All	0.818	0.671	.015	16	view →
UCEC	OS	Quartile	All	0.868	0.961	.003	16	view →
GBM	OS	Median	All	0.334	0.481	.008	15	view →
PRAD	OS	Median	All	0.835	0.923	.018	10	view →
MESO	OS	Tertile	III,IV	0.280	0.451	.017	9	view →
CHOL	DFS	Quartile	All	0.829	0.255	.034	6	view →
LUSC	OS	Tertile	II,III,IV	0.591	0.874	.012	4	view →
TGCT	DFS	Tertile	All	0.790	0.551	.028	4	view →
READ	OS	Tertile	IV	0.491	1.000	.030	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ACTBP12–COAD (DFS)

Open the COAD breakdown →