ACTB

Across TCGA patient cohorts, ACTB RNA expression is significantly associated with the protein abundance of many other proteins, with 14,390 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACTB-associated proteins across cancer lineages are MMP14, PLAU, and P4HA2. Each is linked with ACTB in more than 7 cancer types. Because this analysis shows association rather than direction, both ACTB-to-partner and partner-to-ACTB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACTB versus MMP14 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTB→partner) and Y-score (partner→ACTB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MMP14 →	+0.524	+1.073	<.001	<.001	3	8
GBM	PLAU →	+0.671	+0.300	<.001	<.001	3	8
GBM	P4HA2 →	+0.582	+0.338	<.001	<.001	3	7
PDAC	SERPINH1 →	+0.593	+0.461	<.001	<.001	3	7
GBM	MYH9 →	+0.376	+0.327	<.001	<.001	3	7
OV	RAB31 →	+0.644	+1.064	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,390 associations by consensus.

ACTB vs MMP14 — OV

Explore this scatter interactively →