ACTA2

Across TCGA patient cohorts, ACTA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,370 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ACTA2-associated proteins across cancer lineages are MYL9, P3H3, and PALLD. Each is linked with ACTA2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ACTA2-to-partner and partner-to-ACTA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACTA2 versus MYL9 in UCEC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ACTA2→partner) and Y-score (partner→ACTA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYL9 →	+0.952	+1.643	<.001	<.001	3	10
OV	P3H3 →	+0.763	+1.984	<.001	<.001	3	10
OV	PALLD →	+0.930	+2.135	<.001	<.001	3	10
CCRCC	PCOLCE →	+0.950	+1.489	<.001	<.001	3	10
UCEC	PDLIM7 →	+0.897	+1.924	<.001	<.001	3	10
COAD	RCN3 →	+0.768	+1.201	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,370 associations by consensus.

ACTA2 vs MYL9 — UCEC

Explore this scatter interactively →