Across TCGA patient cohorts, ACSM5 mutation is significantly associated with the RNA expression of many other genes, with 3,448 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACSM5-associated genes across cancer lineages are ZFP92, RNA5SP410, and UBA7. Each is linked with ACSM5 in more than 3 cancer types. Because this analysis shows association rather than direction, both ACSM5-to-partner and partner-to-ACSM5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSM5→partner) and Y-score (partner→ACSM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZFP92 →	-0.657	-4.065	<.001	<.001	3	4
LGG	RNA5SP410 →	+0.618	+7.977	<.001	.007	3	3
UCEC	UBA7 →	-0.729	-1.726	<.001	.006	3	3
UCEC	MX2 →	-0.795	-3.079	<.001	<.001	3	3
SKCM	HSF1 →	+0.387	+2.112	<.001	.002	3	3
UCEC	UBE2L3 →	+0.341	+2.981	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,448 associations by consensus.

Exploration

ACSM5 survival (RNA) · tumor vs normal (RNA) · all ACSM5 data types