Across TCGA patient cohorts, ACSM5 mutation is significantly associated with the total protein of many other genes, with 56 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACSM5-associated genes across cancer lineages are FASN, FOXO3a_pS318_S321, and ACC1. Each is linked with ACSM5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACSM5-to-partner and partner-to-ACSM5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSM5→partner) and Y-score (partner→ACSM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.281	+1.440	.039	.024	3	3
UCEC	FOXO3a_pS318_S321 →	-0.120	-2.575	.005	.001	3	3
UCEC	ACC1 →	+0.328	+2.070	.009	.001	3	3
UCEC	Caspase-7-cleavedD198 →	+0.611	+1.906	.002	.014	3	3
UCEC	eEF2 →	+0.285	+2.321	.021	.033	3	2
UCEC	FoxM1 →	+0.260	+2.070	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

Exploration

ACSM5 survival (RNA) · tumor vs normal (RNA) · all ACSM5 data types