Across TCGA cell cohorts, ACSM5 mutation is significantly associated with the RNA expression of many other genes, with 74 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACSM5-associated genes across cancer lineages are TBL1Y, LCE2A, and TNRC6B. Each is linked with ACSM5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACSM5-to-partner and partner-to-ACSM5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSM5→partner) and Y-score (partner→ACSM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	TBL1Y →	+0.053	+4.643	<.001	.008	3	1
BLOOD_Leukemia	LCE2A →	+0.042	+4.384	<.001	.006	3	1
LARGE_INTESTINE	TNRC6B →	+0.938	+3.064	<.001	.009	3	1
LARGE_INTESTINE	RBM23 →	+0.625	+3.064	.002	.009	3	1
LARGE_INTESTINE	RAI1 →	+0.854	+3.064	.005	.009	3	1
LARGE_INTESTINE	VHL →	+0.844	+3.067	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 74 associations by consensus.

Exploration

ACSM5 survival (RNA) · tumor vs normal (RNA) · all ACSM5 data types