ACSM4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ACSM4 mutation is significantly associated with the RNA expression of many other genes, with 2,847 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ACSM4-associated genes across cancer lineages are OR2S2, OR10G6, and LINC01047. Each is linked with ACSM4 in more than 2 cancer types. Because this analysis shows association rather than direction, both ACSM4-to-partner and partner-to-ACSM4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSM4→partner) and Y-score (partner→ACSM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMOR2S2 →+0.057+4.857<.001.00532
GBMOR10G6 →+0.052+5.614<.001.00132
UCECLINC01047 →+0.089+1.936.005.00132
READRNU6-213P →+0.800+3.400<.001.00632
READOR6K5P →+0.027+4.257.003.00732
READLINC02869 →+0.144+4.176<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,847 associations by consensus.

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