Across TCGA cell cohorts, ACSM2A mutation is significantly associated with the RNA expression of many other genes, with 61 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ACSM2A-associated genes across cancer lineages are GRK7, KIR3DL2, and OR13C3. Each is linked with ACSM2A in more than 1 cancer types. Because this analysis shows association rather than direction, both ACSM2A-to-partner and partner-to-ACSM2A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSM2A→partner) and Y-score (partner→ACSM2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GRK7 →	+0.094	+2.632	<.001	.009	3	2
LARGE_INTESTINE	KIR3DL2 →	+0.033	+2.556	.003	.006	3	2
BLOOD_Leukemia	OR13C3 →	+0.019	+3.874	<.001	.005	3	2
LUNG_NSCLC_LUAD	KRTAP10-5 →	+0.011	+4.078	<.001	.009	3	2
SKIN	OR10H5 →	+0.007	+2.977	<.001	.006	3	2
OESOPHAGUS	CT45A6 →	+0.099	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 61 associations by consensus.

Exploration

ACSM2A survival (RNA) · tumor vs normal (RNA) · all ACSM2A data types