ACSM1

Across TCGA patient cohorts, ACSM1 protein abundance is significantly associated with the RNA expression of many other genes, with 149 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ACSM1-associated genes across cancer lineages are ATG4A, USB1, and WNT2. Each is linked with ACSM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ACSM1-to-partner and partner-to-ACSM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ACSM1 versus ATG4A in BRCA, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ACSM1→partner) and Y-score (partner→ACSM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ATG4A →	+0.457	+0.822	<.001	.002	3	1
BRCA	USB1 →	+0.537	+1.229	.007	.006	3	1
BRCA	WNT2 →	+1.378	+0.891	<.001	<.001	3	1
BRCA	SEC61B →	+0.486	+0.795	<.001	.003	3	1
BRCA	DKK1 →	+1.907	+0.810	<.001	.002	3	1
BRCA	VWA5A →	+1.017	+0.795	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 149 associations by consensus.

ACSM1 vs ATG4A — BRCA

Explore this scatter interactively →